Basic Information
VIS ID
TVIS30015467
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
38753624/40597372 (Hg38)
End
38753648/40597372 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/403709; hsa-mir-10226/Downstream/919792;
Nearest TSS
ENST00000595228/Upstream/31900; ENST00000619697/Downstream/34389;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/153318, chr17-CpG: 69/Downstream/50320
Nearby gene
SMARCE1(No orient, 30351)
Upstream sequence
gttccctcacgtgtctttgtagccaaccccttcctctaccctcagctcctcacaaccactgaactggtttctgtctgtagttttTGGAACAAAGACTTTC
Downstream sequence
GAAGAGAGTCTGTGTGTAAATACCAATGTATGCATGTTGGAATCTCCCCCTCCTTGGCTCCTGTCCTGGGGGTGAAGAAAGATAAAGATTATTGAAAACA
Target sequence
TAAGCAAAGAACAAAAATGGAGCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate