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VISDB
Viral Integration Site DataBase
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TVIS30015473
Basic Information
VIS ID
TVIS30015473
Fusion event
HIV-SMARCE1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
38799819/40643567 (Hg38)
End
38799592/40643567 (Hg38)
Orient
-
Location type
Intronic
Target gene
SMARCE1
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-103a-3p
;
hsa-mir-26b-5p
;
hsa-mir-328-3p
;
hsa-mir-30c-5p
;
hsa-mir-1260b
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-7162-5p
;
hsa-mir-3158-5p
;
hsa-mir-3183
;
hsa-mir-4723-3p
;
hsa-mir-6769b-3p
;
hsa-mir-7110-3p
;
hsa-mir-7111-3p
;
hsa-mir-544a
;
hsa-mir-4684-5p
;
hsa-mir-376a-5p
;
hsa-mir-17-3p
;
hsa-mir-1205
;
hsa-mir-1184
;
hsa-mir-520f-5p
;
hsa-mir-5571-5p
;
hsa-mir-107
;
hsa-mir-8065
;
hsa-mir-376a-2-5p
;
hsa-mir-1256
;
hsa-mir-4487
;
hsa-mir-558
;
hsa-mir-3160-3p
;
hsa-mir-605-3p
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-3910
;
hsa-mir-196a-3p
;
hsa-mir-3182
;
hsa-mir-4774-5p
;
hsa-mir-4490
;
hsa-mir-6870-3p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-4518
;
hsa-mir-1266-5p
;
hsa-mir-5193
;
hsa-mir-4667-3p
;
hsa-mir-6795-3p
;
hsa-mir-6887-3p
Nearest miRNA
hsa-mir-1180/Upstream/449904; hsa-mir-10226/Downstream/873597;
Nearest TSS
ENST00000595228/Upstream/1055;
ENST00000619697/Downstream/2269;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/199513
,
chr17-CpG: 69/Downstream/4125
Upstream sequence
CACAAATGGGCTCTTATATAGCAGTAGCCTTGGGGCTAATACAATGACACTCAATGTTCATGAGAACCAAGGCATAATGCATAGAAAGAATATAGTAGAG
Downstream sequence
AGAGACCAAAATTAGGGTATTTTACCTTGTAAAATTCAATCAAAATATGTGACAATTTCATTTTTACATGCAATTAACAATATCGGTCCTTAATTGTATA
Target sequence
AACTACTTTTCTAGTTTATAGACTTCTTTTTTCATCTAGTTTCCTGATAGCTCTCACCCTTTCAAAATACAACTGCTCATTTCAGCAACAGAACCCTTGGTTTTTGTGAATTATGTGTTGATGTAATCACAAATGGGCTCTTATATAGCAGTAGCCTTGGGGCTAATACAATGACACTCAATGTTCATGAGAACCAAGGCATAATGCATAGAAAGAATATAGTAGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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