Basic Information
VIS ID
TVIS30015474
Fusion event
HIV-LOC105371777 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
39006596/40850344 (Hg38)
End
39006430/40850344 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371777
Nearest miRNA
hsa-mir-1180/Upstream/656681; hsa-mir-10226/Downstream/666820;
Nearest TSS
ENST00000595228/Upstream/27749; ENST00000579136/Downstream/456;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/31136, chr17-CpG: 48/Downstream/12791
Nearby gene
KRT12(No orient, 10833)
Upstream sequence
CATACAAAGCACACTTTAATGACGAATTAGAGGATTCCAAGCTTGCCTTTATAAGTGAATATCTACAGATTTTTTTTTCTTATAAATACTACATGGAAAC
Downstream sequence
CAAGTTACTCTATGTTTTGAAAGCAACTTCTAGTACTCTTTAGATGTATGGGAAAAAGTCCTCAGGTTAATTTCCTTAAGAAAAAGCGTCATGAATTAAA
Target sequence
AAGCCAGTGTTCCATCAGCCATTTTAAGATAACTCAGTTTTGTATCTATGGTTAGGCGATTGCCTACATACAAAGCACACTTTAATGACGAATTAGAGGATTCCAAGCTTGCCTTTATAAGTGAATATCTACAGATTTTTTTTTCTTATAAATACTACATGGAAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate