Basic Information
VIS ID
TVIS30015475
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
39494142/41337890 (Hg38)
End
39494006/41337890 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/1144227; hsa-mir-10226/Downstream/179274;
Nearest TSS
ENST00000595228/Upstream/22195; ENST00000430006/Downstream/12922;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/474041, chr17-CpG: 83/Downstream/189766
Nearby gene
KRT33A(No orient, 8228)
Upstream sequence
AAATGTCATTGCCATCACTTAGATTTGTGTATACATTTACAAAACCATAAAATGCCAGAAGGACATACATTTAATATACATTAATGCATACATTTCATAT
Downstream sequence
GTATGTCCTTCTAGCATTTTATGGTTTTTTAAATGTATATACAAGTCTAAGATTTTTTTAAATACAAACATAAACATGAACTGGCATTTTTCAATCAACT
Target sequence
ACCTTTATACAAATACCTTATTGGAGGGGTCTGAACAAATGTCATTGCCATCACTTAGATTTGTGTATACATTTACAAAACCATAAAATGCCAGAAGGACATACATTTAATATACATTAATGCATACATTTCATAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate