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TVIS30015489
Basic Information
VIS ID
TVIS30015489
Fusion event
HIV-STAT5B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
40414129/42262111 (Hg38)
End
40414092/42262111 (Hg38)
Orient
-
Location type
Intronic
Target gene
STAT5B
miRNAs that regulate target gene
hsa-mir-23b-3p
;
hsa-mir-1229-3p
;
hsa-mir-93-3p
;
hsa-mir-324-3p
;
hsa-mir-134-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-335-3p
;
hsa-mir-6734-5p
;
hsa-mir-1226-5p
;
hsa-mir-6834-5p
;
hsa-mir-526b-5p
;
hsa-mir-6738-5p
;
hsa-mir-5194
;
hsa-mir-1914-3p
;
hsa-mir-423-5p
;
hsa-mir-3184-5p
;
hsa-mir-4762-5p
;
hsa-mir-4789-3p
;
hsa-mir-8485
;
hsa-mir-106b-3p
;
hsa-mir-150-5p
;
hsa-mir-28-5p
;
hsa-mir-182-3p
;
hsa-mir-28-3p
Nearest miRNA
hsa-mir-1180/Upstream/744894; hsa-mir-10226/Downstream/232662;
Nearest TSS
ENST00000595228/Upstream/44240;
ENST00000592536/Downstream/6476;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/77520
,
chr17-CpG: 126/Downstream/13822
Upstream sequence
TTACTTAATTAAATTTTACATGAAATAAGTAAGTCTACTGGGCTCAAAATTGTCTATTTTTAAGGTTGTAATTTTATTTAAATTCTCTTAAAGTATCAAC
Downstream sequence
TCATAATTTACTTTCATTCCTCTTCTTTAAACTCTGTCAAGTGTTAAAAttcttttatttttattctgagacagggtctttctctgtcacccaggctaga
Target sequence
GGTTGTAATTTTATTTAAATTCTCTTAAAGTATCAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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