VISDB Viral Integration Site DataBase

VIS ID

TVIS30015501

Fusion event

HIV-STAT3 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr17

Cytoband

q21.2

Reference genome

Start

End

40507544/42355085 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-20b-5p ; hsa-mir-125b-5p ; hsa-mir-337-3p ; hsa-mir-155-5p ; hsa-mir-93-5p ; hsa-mir-21-5p ; hsa-mir-92a-3p ; hsa-mir-20a-5p ; hsa-let-7e-5p ; hsa-mir-124-3p ; hsa-mir-130b-3p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-874-3p ; hsa-mir-4516 ; hsa-mir-17-5p ; hsa-mir-200a-3p ; hsa-mir-544a ; hsa-mir-181a-5p ; hsa-mir-1234-3p ; hsa-mir-1181 ; hsa-mir-6878-5p ; hsa-mir-5681a ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4270 ; hsa-mir-4441 ; hsa-mir-922 ; hsa-mir-6760-5p ; hsa-mir-1288-5p ; hsa-mir-6871-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-1178-3p ; hsa-mir-7158-5p ; hsa-mir-4684-5p ; hsa-mir-138-2-3p ; hsa-mir-371b-3p ; hsa-mir-548n ; hsa-mir-6875-3p ; hsa-mir-5581-3p ; hsa-mir-4778-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-877-3p ; hsa-mir-618 ; hsa-mir-6807-5p ; hsa-mir-4720-3p ; hsa-mir-6762-3p ; hsa-mir-4804-3p ; hsa-mir-6872-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6789-3p ; hsa-mir-500b-3p ; hsa-mir-4438 ; hsa-mir-519d-3p ; hsa-mir-520c-3p ; hsa-mir-125a-5p ; hsa-mir-21-3p ; hsa-mir-519a-3p ; hsa-mir-148a-3p ; hsa-mir-223-3p ; hsa-let-7c-5p ; hsa-mir-29b-1-5p ; hsa-mir-23a-3p ; hsa-mir-323a-3p ; hsa-mir-375 ; hsa-mir-124-5p ; hsa-mir-29b-3p ; hsa-let-7a-5p ; hsa-mir-340-5p ; hsa-mir-410-5p

Nearest miRNA

hsa-mir-1180/Upstream/837868; hsa-mir-10226/Downstream/139688;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/42156, chr17-CpG: 87/Downstream/32734

Nearest cancer related gene

STAT3(TSG, No orient, 0)

Upstream sequence

TCTTCTCCTTACAGGCTGCTTAGCTACAAACCATATTTAATTAACAGCAGTCACAGGAGATGACTAGCCAAAGTGTCTAGGAAAATCACTGCCAAGCAGC

Downstream sequence

GTGGGTGTAATCCTGTTTTCTATAACTGAAGAGAAAAGAAAAAAATGAAACAGCAAGTCATCAAAGACTTTTTGGACTTTTCAAAACAGGAATTTCTCAG

Target sequence

TTTACTGTAACTGTTTTACTGGAAAAGACCTCAAAGAGCCCATGTTATTTCACAATTTCAATTTTGGTTTTTCAAATTACAAGTTAATCTAAAGAACTCCACTAAGTTCTAACTACATTACTTCATATCTACGGAATAATTCTAAGCCTGTGGGTTTTTAAAAAAAttttattagacattctagaattgggcaacacttcattcaatgccataggatgaatgttcTCCCCAAGCCTGTGACTTAATAACTActtc