Basic Information
VIS ID
TVIS30015509
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43235665/45158298 (Hg38)
End
43235846/45158298 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/43865; hsa-mir-10226/Downstream/317065;
Nearest TSS
ENST00000595228/Upstream/9796; ENST00000591070/Downstream/1157;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/8049, chr17-CpG: 83/Downstream/2595
Nearby gene
HEXIM2(No orient, 2598)
Upstream sequence
TTCACAGCCACAACCAGTGGGCACCCTGAGAGACTGATCCTCATTCAGCCTACTTGGATGGCTCTTTTGTGATGCTATGGACAACTAAGGCCACACTTTG
Downstream sequence
GTCATAAAAGCATAATGCAACTCATCTGAGAGGGGAGAGCTGAAAAGGAAGTTGAAAGTCTGGTTGAACAGTAGATGAACAATAGACTAAGCAGCAAAAT
Target sequence
GTAAGGCAGGCTTTCCAACTGCCCCAATGATCTTTGAAGCATTCCTTGTGAAGTTCTCATATAACAAAGTTACAAGGAGTAAGTGTTTACATAGCGACTTAAGACTAGTTACTCCTCTAGGTATTTATGAGGGAGACAGTGCTGATACCATTTTCAAATGAATATAGAGTTTGTAGAATTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate