Basic Information
VIS ID
TVIS30015511
Fusion event
HIV-KANSL1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
End
44126208/46048989 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-106b-5p ; hsa-mir-149-5p ; hsa-mir-23b-3p ; hsa-mir-17-5p ; hsa-mir-154-3p ; hsa-mir-487a-3p ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-130b-5p ; hsa-mir-1287-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-555 ; hsa-mir-6881-5p ; hsa-mir-6835-5p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6799-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6871-5p ; hsa-mir-6732-5p ; hsa-mir-449b-3p ; hsa-mir-5683 ; hsa-mir-4664-3p ; hsa-mir-1180-3p ; hsa-mir-5585-3p ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-548g-3p ; hsa-mir-4282 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-192-3p ; hsa-mir-627-5p ; hsa-mir-127-5p ; hsa-mir-921 ; hsa-mir-3606-5p ; hsa-mir-924 ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-3174 ; hsa-mir-155-5p ; hsa-mir-365a-3p ; hsa-mir-365b-3p ; hsa-mir-4762-3p ; hsa-mir-4756-3p ; hsa-mir-7855-5p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-4524a-3p ; hsa-mir-4768-3p ; hsa-mir-4700-3p ; hsa-mir-4524b-3p ; hsa-mir-7111-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-3974 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-7975 ; hsa-mir-5571-3p ; hsa-mir-4789-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-4528 ; hsa-mir-4742-3p ; hsa-mir-548av-3p ; hsa-mir-521 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6870-3p ; hsa-mir-5088-3p
Nearest miRNA
hsa-mir-1180/Upstream/573554; hsa-mir-10226/Downstream/924028;
Upstream sequence
TCTTTTAAACTTATTTAGCTAATCAGACTTTAGATATTAACTCAGTATTTATTCTAAGACAGACAAGGAATAGGACCATGTAACTGAGCTCAGACCCATC
Downstream sequence
CCAGCCACTCGAAGAGTTAGAGGGAAATCTCTTAGTTGCAATCTTTTAGTGGTACCCTCTGGTTTGGTAGATCTGTTGCAGTCTTTTTGGAGAATTCTAA
Target sequence
CTTTGGCATGTAAATATATTTAGCTTCATTAATTGAAAAAAAAAACTTCTTTTAAACTTATTTAGCTAATCAGACTTTAGATATTAACTCAGTATTTATTCTAAGACAGACAAGGAATAGGACCATGTAACTGAGCTCAGACCCATC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate