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TVIS30015512
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
46250430
46029916
46225389
45894382
46028334
46065381
46070165
46024523
46028153
46050202
46052524
46071607
46073924
46056159
46058474
46030182
46032401
46062548
46064715
46034180
46035862
46043972
46045064
46028515
46029571
46042129
46042611
46035313
46035770
46054584
46054812
46045715
46045864
46036599
46036739
46072406
Basic Information
VIS ID
TVIS30015512
Fusion event
HIV-KANSL1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
44149772/46072406 (Hg38)
End
44149942/46072406 (Hg38)
Orient
+
Location type
Intronic
Target gene
KANSL1
miRNAs that regulate target gene
hsa-mir-130b-3p
;
hsa-mir-148a-3p
;
hsa-mir-106b-5p
;
hsa-mir-149-5p
;
hsa-mir-23b-3p
;
hsa-mir-17-5p
;
hsa-mir-154-3p
;
hsa-mir-487a-3p
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-3606-3p
;
hsa-mir-130b-5p
;
hsa-mir-1287-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-555
;
hsa-mir-6881-5p
;
hsa-mir-6835-5p
;
hsa-mir-6825-5p
;
hsa-mir-6883-5p
;
hsa-mir-6799-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6871-5p
;
hsa-mir-6732-5p
;
hsa-mir-449b-3p
;
hsa-mir-5683
;
hsa-mir-4664-3p
;
hsa-mir-1180-3p
;
hsa-mir-5585-3p
;
hsa-mir-1322
;
hsa-mir-1272
;
hsa-mir-548g-3p
;
hsa-mir-4282
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-192-3p
;
hsa-mir-627-5p
;
hsa-mir-127-5p
;
hsa-mir-921
;
hsa-mir-3606-5p
;
hsa-mir-924
;
hsa-mir-6806-3p
;
hsa-mir-3928-5p
;
hsa-mir-3174
;
hsa-mir-155-5p
;
hsa-mir-365a-3p
;
hsa-mir-365b-3p
;
hsa-mir-4762-3p
;
hsa-mir-4756-3p
;
hsa-mir-7855-5p
;
hsa-mir-539-3p
;
hsa-mir-485-3p
;
hsa-mir-4524a-3p
;
hsa-mir-4768-3p
;
hsa-mir-4700-3p
;
hsa-mir-4524b-3p
;
hsa-mir-7111-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-3974
;
hsa-mir-384
;
hsa-mir-3685
;
hsa-mir-4753-3p
;
hsa-mir-6873-3p
;
hsa-mir-7975
;
hsa-mir-5571-3p
;
hsa-mir-4789-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-8067
;
hsa-mir-6508-5p
;
hsa-mir-4528
;
hsa-mir-4742-3p
;
hsa-mir-548av-3p
;
hsa-mir-521
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-6870-3p
;
hsa-mir-5088-3p
Nearest miRNA
hsa-mir-1180/Upstream/596971; hsa-mir-10226/Downstream/900611;
Nearest TSS
ENST00000595228/Upstream/21712;
ENST00000572973/Downstream/22235;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/89242
,
chr17-CpG: 128/Downstream/120660
Upstream sequence
TTTTACTTTATTCAATTAATGCCATGTCACACCTGCTTGCAATGTCATTTTTTAAATGTATCACATTCGTTTGGCTAGAAAAGTCAACAGTTCAGTTTTG
Downstream sequence
ATTCACCAAAATATTGCTGGCCTATAAATAGTATACTAGCCATTTCCATTAGCTAGCACCATGGCCATAAAATTGTACTAAACAAGAAGTGGAATGTTCT
Target sequence
GTTAGTTATTCCCTTTCTGACAAACATTAAAATGGAAAGAAAATGCTAACTGGGTGACAGGAATTTAACTTATTCCTGGGTTAAAATAGTTTTTGACTTTGTATGATTGATTTCATGTCTCAAGCCCACCCCACCCCCATTTCAATGATACTGAGCATAGTTTCGCTTAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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