Basic Information
VIS ID
TVIS30015514
Fusion event
HIV-EFCAB13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
45468901/47391535 (Hg38)
End
45468859/47391535 (Hg38)
Orient
-
Location type
Exonic
Target gene
EFCAB13
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1180/Upstream/418435; hsa-mir-10226/Downstream/641347;
Nearest TSS
ENST00000595228/Upstream/13719; ENST00000533573/Downstream/31991;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/67461, chr17-CpG: 120/Downstream/31879
Upstream sequence
GCGTTGCCTGGTGTCATTAAAGCCATTGATAAAATTAAAGATAAAAATGTGGATTATGAGGATCTAAATACTTGTCTTCAAAATTTTGGTATTTACCTTT
Downstream sequence
CTAAGCCAGAATTTAAGAAGATCACAGAACTGACTGAAGCTGGTGGTGAGTGATATATTTTCAGGCAAACTGCATTGACACATCTGGAAGGAGGGTCAAT
Target sequence
AGGATCTAAATACTTGTCTTCAAAATTTTGGTATTTACCTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate