Basic Information
VIS ID
TVIS30015520
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
48937908/50860547 (Hg38)
End
48937706/50860547 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/91817; hsa-mir-1250/Downstream/6030723;
Nearest TSS
ENST00000595228/Upstream/18921; ENST00000506394/Downstream/5798;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/19586, chr17-CpG: 183/Downstream/5161
Nearby gene
TOB1(No orient, 1678)
Upstream sequence
agctataatcccagctattcaggagagtgagacaggagaatcgctttagtggaggttgcagtaagccaagatggcccctttgcactccagcctgggtgac
Downstream sequence
agagtgagaccttgtctcaaaataaaaTGAATATATTAGTGCTCCAGACAGTTTCAAATTCTATTGTTgaccaggcgcaatggctcatgcctgtaatcag
Target sequence
gggcggatcaccttagttcaggagtttgagaccagcccaggcaacgtggcgaaaccctgcctctacaaaaaatacaaaaattagcagggaacggtggcacgcagctataatcccagctattcaggagagtgagacaggagaatcgctttagtggaggttgcagtaagccaagatggcccctttgcactccagcctgggtgac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate