VISDB Viral Integration Site DataBase

VIS ID

TVIS30015523

Fusion event

HIV-SRSF1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr17

Cytoband

q22

Reference genome

Start

End

56080359/58003128 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-7-5p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-505-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-744-5p ; hsa-mir-193b-3p ; hsa-mir-423-3p ; hsa-mir-149-5p ; hsa-mir-335-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-607 ; hsa-mir-1305 ; hsa-mir-4709-3p ; hsa-mir-155-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-6823-3p ; hsa-mir-377-5p ; hsa-mir-2114-3p ; hsa-mir-7113-5p ; hsa-mir-4762-5p ; hsa-mir-6782-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-6715a-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6753-5p ; hsa-mir-377-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-4653-3p ; hsa-mir-4424 ; hsa-mir-622 ; hsa-mir-6514-5p ; hsa-mir-4802-5p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-338-5p ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3681-3p ; hsa-mir-552-5p ; hsa-mir-6792-5p ; hsa-mir-107 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1255b-2-3p ; hsa-mir-6776-3p ; hsa-mir-33a-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-508-3p ; hsa-mir-4724-5p ; hsa-mir-6734-3p ; hsa-mir-3667-3p ; hsa-mir-34c-3p ; hsa-mir-500a-5p ; hsa-mir-34b-3p ; hsa-mir-4668-3p ; hsa-mir-548c-3p ; hsa-mir-9-5p ; hsa-mir-1227-3p ; hsa-mir-25-5p ; hsa-mir-4252 ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-508-5p ; hsa-mir-550b-2-5p ; hsa-mir-6087 ; hsa-mir-658 ; hsa-mir-766-3p ; hsa-mir-5186

Nearest miRNA

hsa-mir-10226/Upstream/1111773; hsa-mir-1250/Downstream/328104;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/14438, chr17-CpG: 139/Downstream/3315

Nearest cancer related gene

SRSF1(OG, No orient, 0)

Upstream sequence

CTAATACATCTGTGCTGATGTTAACATTTAATACTTACCTTTTTTTGAGATGAGTTTCATTGAGAATATCAAAAGCTATCTCCAAGTGAACATTAGTAGC

Downstream sequence

CATCAACCAATTTTGCACAAAAGCCTATGTTGTCTATGACCACCAGAAAATAAGCAGCATCTATAGTTTTTTAACCACTTTATAACAAAGTAGAGAAGCT

Target sequence

gagactctgtctcaaaaacaaaaaaCAGTTCTAATACATCTGTGCTGATGTTAACATTTAATACTTACCTTTTTTTGAGATGAGTTTCATTGAGAATATCAAAAGCTATCTCCAAGTGAACATTAGTAGC