Basic Information
VIS ID
TVIS30015525
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
56223012/58145651 (Hg38)
End
56222981/58145651 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA17B
Nearest miRNA
hsa-mir-10226/Upstream/1254296; hsa-mir-1250/Downstream/185581;
Nearest TSS
ENST00000595228/Upstream/62236; ENST00000268912/Downstream/2798;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/61518, chr17-CpG: 52/Downstream/11309
Nearby gene
OR4D1(No orient, 9502)
Upstream sequence
tgtttcctatgtggtttaaaagacaaatgcataaaataataattataagtttatgttaaaatgcacacatatataaaaaggaatttatgagagtaacaac
Downstream sequence
ataaaggtggagggaaggaatgaaatataggcagtgttaatgtatattattgaagctaagttgttatcatactagattcagattagcttcaaattagatt
Target sequence
tatataaaaaggaatttatgagagtaacaac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate