Basic Information
VIS ID
TVIS30015529
Fusion event
HIV-VMP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
57876956/59799595 (Hg38)
End
57877092/59799595 (Hg38)
Orient
+
Location type
Intronic
Target gene
VMP1
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-296-3p ; hsa-mir-25-3p ; hsa-mir-4776-3p ; hsa-mir-744-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-7159-5p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-4694-5p ; hsa-mir-5186 ; hsa-mir-7978 ; hsa-mir-181a-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-1324 ; hsa-mir-4709-5p ; hsa-mir-4272 ; hsa-mir-6856-3p ; hsa-mir-513b-3p ; hsa-mir-505-3p ; hsa-mir-421 ; hsa-mir-3161 ; hsa-mir-622 ; hsa-mir-4761-5p ; hsa-mir-624-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-138-2-3p ; hsa-mir-4282 ; hsa-mir-4698 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-555 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-3925-3p ; hsa-mir-766-3p ; hsa-mir-5680 ; hsa-mir-4506 ; hsa-mir-150-3p
Nearest miRNA
hsa-mir-10226/Upstream/433441; hsa-mir-1250/Downstream/41671;
Nearest TSS
ENST00000595228/Upstream/25841; ENST00000588617/Downstream/38033;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/91848, chr17-CpG: 73/Downstream/93086
Upstream sequence
TATAGCTAGTAATTTAAAATTTATTAACTATTTTCTTTGTTTTACAATCACTTTATTTCAACAATATCCCTACTTTTTTGGTAATTCTAGAATTTATTTC
Downstream sequence
gcgggaggatcacctgaggtcaggagtttgagaccagcctggccaacatggtaaaaccccatctctactaaagatacaaaaattagccaggtgtggtggc
Target sequence
CTAACCACAGTCTTTATCCCGTGACCTTATTATGTTATAATTCAATAACAATAAATAATGTGTGACTTAAAAATATGCTTCACTTggccgggcgcagtggctcacgcctgaaatcccagcattttgggaggccaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate