Basic Information
VIS ID
TVIS30015533
Fusion event
HIV-CEP95 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
62523069/64526951 (Hg38)
End
62522759/64526951 (Hg38)
Orient
-
Location type
Intronic
Target gene
CEP95
Nearest miRNA
hsa-mir-10226/Upstream/25638; hsa-mir-1250/Downstream/253808;
Nearest TSS
ENST00000595228/Upstream/785; ENST00000579478/Downstream/89;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/19503, chr17-CpG: 112/Downstream/134340
Upstream sequence
caagtggttgagatgggaggatcactggaacccagtaggcagaggttacagtgagcccagctagcaccactgcactccagcctgggtgacagagtgagat
Downstream sequence
cctgtctcaaaataaaaGTAAATAATTAAACATGCATAAGCGTCTGAAAACTTGTTATTAGTGACTGTCAAAGGAAGCTTTTTTAAAGGTCTGCCTACTC
Target sequence
TAGCACTGATATACACCTTTTTAAAACTAAACATGTATgccaggtgtggtggctcacaactgtaattccaacactttgagaggctgaggcaggtggatcacttaagcccaggagtttgagaccagcctgggcaacatggcaaaaccccatctctacaaaaaataaaagattagccaggcttggtggcatatgcctgtaatcccagctactcaagtggttgagatgggaggatcactggaacccagtaggcagagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate