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TVIS30015535
Basic Information
VIS ID
TVIS30015535
Fusion event
HIV-PITPNC1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
65386003/67389887 (Hg38)
End
65385824/67389887 (Hg38)
Orient
-
Location type
Intronic
Target gene
PITPNC1
miRNAs that regulate target gene
hsa-mir-126-3p
;
hsa-mir-335-5p
;
hsa-mir-142-3p
;
hsa-mir-7-5p
;
hsa-mir-192-5p
;
hsa-mir-26b-5p
;
hsa-mir-1277-5p
;
hsa-mir-6083
;
hsa-mir-190a-3p
;
hsa-mir-4789-5p
;
hsa-mir-4672
;
hsa-mir-5011-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-6768-5p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-369-3p
;
hsa-mir-548v
;
hsa-mir-548d-3p
;
hsa-mir-548au-3p
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-450b-5p
;
hsa-mir-6516-5p
;
hsa-mir-6811-5p
;
hsa-mir-6511b-5p
;
hsa-mir-488-3p
;
hsa-mir-657
;
hsa-mir-4635
;
hsa-mir-3665
;
hsa-mir-4678
;
hsa-mir-935
;
hsa-mir-5003-3p
;
hsa-mir-140-3p
;
hsa-mir-497-3p
;
hsa-mir-548t-3p
;
hsa-mir-548ap-3p
;
hsa-mir-548aa
Nearest miRNA
hsa-mir-10226/Upstream/602719; hsa-mir-1250/Downstream/81602;
Nearest TSS
ENST00000595228/Upstream/10921;
ENST00000584554/Downstream/67651;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/10872
,
chr17-CpG: 43/Downstream/327765
Upstream sequence
tcctgcctcagtctcccgagtagctgggactacaggcacgtgccaccacgcccggctaattgtttgtatttttagtagagacggggtttcactgtggtag
Downstream sequence
ccaggatggtctcgaactcctgacctcgtgatccacccacctcggcctcccaaagtgctgggattacagacgcgagccaccgtgcccggccAAAGCTGTT
Target sequence
tcactctgttgcccaggctagagtgctatggcgcaatctcggctcactgcaccctccgcttcctgggttcaagcaattctcctgcctcagtctcccgagtagctgggactacaggcacgtgccaccacgcccggctaattgtttgtatttttagtagagacggggtttcactgtggtag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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