VISDB Viral Integration Site DataBase

VIS ID

TVIS30015536

Fusion event

HIV-PRKAR1A integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr17

Cytoband

q24.2

Reference genome

Start

End

66523960/68528146 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-16-5p ; hsa-mir-1296-5p ; hsa-mir-324-3p ; hsa-mir-204-5p ; hsa-mir-96-5p ; hsa-mir-25-3p ; hsa-mir-24-2-5p ; hsa-mir-24-1-5p ; hsa-mir-6504-3p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-323a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-552-5p ; hsa-mir-3658 ; hsa-mir-7515 ; hsa-mir-580-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-1246

Nearest miRNA

hsa-mir-10226/Upstream/103598; hsa-mir-1250/Downstream/571396;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/15069, chr17-CpG: 135/Downstream/71831

Nearest cancer related gene

PRKAR1A(TSG, No orient, 0)

Upstream sequence

ACATTCACAGTTATTTCCTCTGTGACTTCCCGTCTCTCTTGTTCCATCATTGAGTTGATTGGTTCAGAAAAGTGAGTACTTCCAACAATACATTTCCTCT

Downstream sequence

GTGGAAAGATTAGGTATCATTTGCTGGCATCCTCTGAAAACATGCCAGAAGTTTGTTGAAATTTAGAGTAAAGCAGATTAATTGAAGATATTCTTTTGTG

Target sequence

TTTGTTATTTTTATTTTTAGGGAAGCACACTGAGAAAGCGGAAGATGTATGAGGAATTCCTTAGTAAAGTCTCTATTTTAGGTGAGTTGTAAAGTGTGTTAACTTTGCTAGTATGTGAGATACCCCTGAATTAGAATTGGATGGACTTGGGAAAAGCCTTCTGAAAGTATAATTGCTACTCATTCCCCCTGAAAAGACAGAAGGGCTGAAAGTCCTTCTGACTGTGGACATTCACAGTTATTTCCTCTGTGACTT