Basic Information
VIS ID
TVIS30015537
Fusion event
HIV-SLC9A3R1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
72751128/74754989 (Hg38)
End
72751191/74754989 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC9A3R1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-let-7b-5p ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-1249-5p ; hsa-mir-1321 ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-3150b-3p ; hsa-mir-3612 ; hsa-mir-4276 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4689 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4779 ; hsa-mir-4784 ; hsa-mir-5007-5p ; hsa-mir-5190 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6797-5p ; hsa-mir-6858-5p ; hsa-mir-765
Nearest miRNA
hsa-mir-10226/Upstream/6290; hsa-mir-1250/Downstream/651080;
Nearest TSS
ENST00000595228/Upstream/6077; ENST00000578958/Downstream/7014;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/5176, chr17-CpG: 49/Downstream/21116
Nearest cancer related gene
SLC9A3R1(TSG, No orient, 0)
Upstream sequence
aagtactaaccttgcctgtctcatttaatccacatgaccaccagtgaggcagatattggccccattctctgcctatggaggctgaggcttgatcagttaa
Downstream sequence
tcttggaacccaaccctctgactctagtgcctgcacAGCCATTTGGCCACATGAGTAGGCTGTGCTTGAAGCCTGACTCTGCCAGGTGTTTCTGCCCATC
Target sequence
ggtggccatggcgggtcccaggactctgagctagcgactcctcccacacagcgcaggggtgtg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate