VISDB Viral Integration Site DataBase

VIS ID

TVIS30015540

Fusion event

HIV-GRB2 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

73398590/75402237 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-433-3p ; hsa-mir-378a-3p ; hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-7-5p ; hsa-mir-93-5p ; hsa-mir-16-5p ; hsa-mir-92b-3p ; hsa-mir-100-5p ; hsa-mir-376c-3p ; hsa-mir-27a-3p ; hsa-mir-200a-3p ; hsa-mir-541-5p ; hsa-mir-6834-5p ; hsa-mir-3915 ; hsa-mir-5196-5p ; hsa-mir-6787-5p ; hsa-mir-4747-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6077 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6875-5p ; hsa-mir-4419a ; hsa-mir-3126-5p ; hsa-mir-3928-3p ; hsa-mir-9500 ; hsa-mir-6165 ; hsa-mir-5586-3p ; hsa-mir-3934-5p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-2054 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-6081 ; hsa-mir-6783-5p ; hsa-mir-4779 ; hsa-mir-4519 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-583 ; hsa-mir-4282 ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-329-3p ; hsa-mir-411-5p ; hsa-mir-96-3p ; hsa-mir-1281 ; hsa-mir-18a-3p ; hsa-mir-1913 ; hsa-mir-221-5p ; hsa-mir-22-3p ; hsa-mir-3120-3p ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-3194-3p ; hsa-mir-324-3p ; hsa-mir-4438 ; hsa-mir-4632-3p ; hsa-mir-484 ; hsa-mir-5197-3p ; hsa-mir-545-3p ; hsa-mir-558 ; hsa-mir-660-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-760 ; hsa-mir-8073

Nearest miRNA

hsa-mir-10226/Upstream/653538; hsa-mir-1250/Downstream/3832;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/112464, chr17-CpG: 77/Downstream/2899

Upstream sequence

aaagcccattttataacaaagtgatgaatatctcctgtaatttactgactatggtactgagagtgaaaaacaaaacagttatatgggtactggaagtata

Downstream sequence

TAAAGCCACACAGCAGTCTTATTATTTATGGCTGCATTTGGTAACAACAGTTTTGATCCTTAGACCATCTGTATCAAAATccacccattcagagactgat

Target sequence

gtttttactgagcgctattgctttcacaccactgtaaagctgaaaaatcTTTCGTCTGAGTCTACAGACTCAGAAGAATTCTCTGGTAGGCAAATTAATGACCCTATTAAGTATAAATTTCAAGTTAAATCACTCCACATCACAGTATTAAGAATGCTAAAAAATTTACACATGTAAAAATGAATCATGCTTATAGTCACTCATTCCATTAGGCTATTCTAAATACTGACTTTGTGTATACACAGAAAAATGTAA