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TVIS30015545
Basic Information
VIS ID
TVIS30015545
Fusion event
HIV-ACOX1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
73951646/75955565 (Hg38)
End
73951575/75955565 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACOX1
miRNAs that regulate target gene
hsa-mir-92b-5p
;
hsa-mir-615-3p
;
hsa-mir-3122
;
hsa-mir-3913-5p
;
hsa-mir-155-5p
;
hsa-mir-153-5p
;
hsa-mir-365b-3p
;
hsa-mir-365a-3p
;
hsa-mir-1273e
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-2467-3p
;
hsa-mir-1827
;
hsa-mir-219b-3p
;
hsa-mir-4649-3p
;
hsa-mir-1247-3p
;
hsa-mir-3919
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-3123
;
hsa-mir-302f
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-450a-1-3p
;
hsa-mir-6796-5p
;
hsa-mir-7109-5p
;
hsa-mir-7977
;
hsa-mir-6742-5p
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-3151-5p
;
hsa-mir-491-5p
;
hsa-mir-6885-5p
;
hsa-mir-328-5p
;
hsa-mir-6887-5p
;
hsa-mir-6795-5p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-383-3p
;
hsa-mir-595
;
hsa-mir-7855-5p
;
hsa-mir-548s
;
hsa-mir-3926
;
hsa-mir-3190-5p
;
hsa-mir-6849-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-6807-5p
;
hsa-mir-6788-3p
;
hsa-mir-6499-3p
;
hsa-mir-4474-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6787-3p
;
hsa-mir-342-3p
;
hsa-mir-3065-3p
;
hsa-mir-1228-3p
;
hsa-mir-216b-5p
;
hsa-mir-216a-5p
;
hsa-mir-619-5p
;
hsa-mir-5004-3p
;
hsa-mir-4665-3p
;
hsa-mir-636
;
hsa-mir-6778-3p
;
hsa-mir-150-5p
;
hsa-mir-7107-5p
;
hsa-mir-1234-3p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-520f-3p
;
hsa-mir-302c-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-1293
;
hsa-mir-3165
;
hsa-mir-339-5p
;
hsa-mir-363-5p
;
hsa-mir-4421
;
hsa-mir-4483
;
hsa-mir-5699-3p
;
hsa-mir-6134
;
hsa-mir-6745
;
hsa-mir-6748-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6771-3p
Nearest miRNA
hsa-mir-10226/Upstream/170958; hsa-mir-1250/Downstream/142454;
Nearest TSS
ENST00000595228/Upstream/6033;
ENST00000590676/Downstream/24;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/14229
,
chr17-CpG: 67/Downstream/23325
Upstream sequence
ATTACCTTCTAAAAGAACAGACCATTCTAACCCTATTGTGAGTAACAGCCACTCAACTCCACTGTTTGATGCCTCTGCTTTATTTTCTATCAAAACATAC
Downstream sequence
CTGGGCATACTTCATCAGCATGTTTTCTCTGGGAATACGATGGTTGTCCATTTTGAGGTAGCCATTGTCTATCTCATCATAACCAAATTTGGGGCCGATG
Target sequence
ACCCTATTGTGAGTAACAGCCACTCAACTCCACTGTTTGATGCCTCTGCTTTATTTTCTATCAAAACATAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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