Basic Information
VIS ID
TVIS30015547
Fusion event
HIV-SRP68 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
74058353/76062272 (Hg38)
End
74058311/76062272 (Hg38)
Orient
-
Location type
Intronic
Target gene
SRP68
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-320b ; hsa-mir-92b-3p ; hsa-mir-365a-3p ; hsa-mir-320a ; hsa-mir-221-3p ; hsa-mir-3653-5p ; hsa-mir-3140-5p ; hsa-mir-888-3p ; hsa-mir-3912-3p ; hsa-mir-548an
Nearest miRNA
hsa-mir-10226/Upstream/277665; hsa-mir-1250/Downstream/35747;
Nearest TSS
ENST00000595228/Upstream/1530; ENST00000329003/Downstream/1750;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/39695, chr17-CpG: 45/Downstream/9821
Upstream sequence
gctactcgggaggctgaggcaggagaattgcttgaaactgggaggcagaggttgcaatgggctgagactgcaccactgcattccaatctgggcgacagag
Downstream sequence
tgagactctgtctcagaaaaaaaaaaaaaaaaatttagccaggtgtggtggtgtgcacctctagtcccaactactcaggaggccatggcaggaggactgc
Target sequence
gggctgagactgcaccactgcattccaatctgggcgacagag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate