Basic Information
VIS ID
TVIS30015548
Fusion event
HIV-LOC105371896 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
74254832/76258751 (Hg38)
End
74254713/76258751 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371896
Nearest miRNA
hsa-mir-10226/Upstream/160675; hsa-mir-1250/Downstream/477699;
Nearest TSS
ENST00000595228/Upstream/18378; ENST00000587913/Downstream/6451;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17621, chr17-CpG: 126/Downstream/6295
Upstream sequence
gtgagctgcattgcaccactgcactgcagctggaatgacattgagacactcttaaaaaaaaaaaaaaGGGCGGGCCAGGTGGGAAAGCTGCCTTGTATCT
Downstream sequence
GAAGTCAGTGCCTGCCACAACAATAGGCCTCTTGTGTTTTGGACATGAAGCTATAGTGGCCTAGCTCCAGGCCCATCCATTTCTGTCCTCCCCAGAGAAA
Target sequence
ccgggaggtcgaggctgcagtgagctgcattgcaccactgcactgcagctggaatgacattgagacactcttaaaaaaaaaaaaaaGGGCGGGCCAGGTGGGAAAGCTGCCTTGTATCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate