Basic Information
VIS ID
TVIS30015550
Fusion event
HIV-MFSD11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
74767214/76771132 (Hg38)
End
74767261/76771132 (Hg38)
Orient
+
Location type
Intronic
Target gene
MFSD11
miRNAs that regulate target gene
hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-371a-5p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6778-3p
Nearest miRNA
hsa-mir-10226/Upstream/34584; hsa-mir-1250/Downstream/318285;
Nearest TSS
ENST00000595228/Upstream/1941; ENST00000590070/Downstream/1965;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/32992, chr17-CpG: 254/Downstream/96956
Upstream sequence
tgtctctaacaacaacaaaaaaacaatcattggccattggtgattgatttaatctccagccttccctccctgaagtgggagtgaaaggggcctggaagtt
Downstream sequence
ctctatcctaggccaacccctctctccccaagggttgcccccttagcgtaaacttcagtatggttgaaagtggctctttctgaataactaatgtccctcg
Target sequence
ctagccctcagggcttggtctttctgggaaccagcctcatcctgaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate