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TVIS30015551
Basic Information
VIS ID
TVIS30015551
Fusion event
HIV-SEPTIN9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
75445908/77449826 (Hg38)
End
75446126/77449826 (Hg38)
Orient
+
Location type
Intronic
Target gene
SEPTIN9
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-186-5p
;
hsa-mir-10a-5p
;
hsa-mir-5587-5p
;
hsa-mir-670-5p
;
hsa-mir-6791-5p
;
hsa-mir-4292
;
hsa-mir-4308
;
hsa-mir-216b-3p
;
hsa-mir-4802-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-6500-3p
;
hsa-mir-4717-3p
;
hsa-mir-3614-5p
;
hsa-mir-128-1-5p
;
hsa-mir-128-2-5p
;
hsa-mir-1914-3p
;
hsa-mir-3144-5p
;
hsa-mir-3184-5p
;
hsa-mir-3191-3p
;
hsa-mir-3677-3p
;
hsa-mir-423-5p
;
hsa-mir-4652-5p
;
hsa-mir-4655-3p
;
hsa-mir-4710
;
hsa-mir-491-5p
;
hsa-mir-5194
;
hsa-mir-6734-5p
;
hsa-mir-6738-5p
;
hsa-mir-6781-5p
;
hsa-mir-6795-3p
;
hsa-mir-6804-5p
;
hsa-mir-6810-5p
;
hsa-mir-6826-3p
;
hsa-mir-6882-3p
;
hsa-mir-6887-3p
Nearest miRNA
hsa-mir-10226/Upstream/52772; hsa-mir-1250/Downstream/2257350;
Nearest TSS
ENST00000595228/Upstream/22870;
ENST00000590917/Downstream/741;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/47381
,
chr17-CpG: 35/Downstream/1569
Nearest cancer related gene
SEPTIN9
(OG, No orient, 0)
Upstream sequence
TGGGCTGCAGACAGTGGAAAAGACAGGCTCTTCTCACTCCCAGTGCTGGGGAAATTAGCTTCTTGGAGGAAGGGGGAGCTGTATTTTCTGAGTGGCCGCA
Downstream sequence
GACACTCCCCCGGCTCTGGCCTGGCGCCCGGAGACCAGTAGCAGCAGCTCCCCACGGCCGTTCACTGTGAGGGTGGGGAGGGCCGTGGGACCAGGAGGCC
Target sequence
CTTCCTGGCCTAGACGTGTGTGTCTTGctgtaattttggcgactggtgttggtggtgcccattttatggatggggaaggtcaaattccacagatattgagtgacaggcccagggccttggatttcagtgtttgactcagaacccaggtctctgatctgccaccagcctccctcccattCAGATGGGAACAGGGACTCCGGGCATGCAGTCTTCTCCCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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