Basic Information
VIS ID
TVIS30015551
Fusion event
HIV-SEPTIN9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
End
75446126/77449826 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10226/Upstream/52772; hsa-mir-1250/Downstream/2257350;
Nearest cancer related gene
SEPTIN9(OG, No orient, 0)
Upstream sequence
TGGGCTGCAGACAGTGGAAAAGACAGGCTCTTCTCACTCCCAGTGCTGGGGAAATTAGCTTCTTGGAGGAAGGGGGAGCTGTATTTTCTGAGTGGCCGCA
Downstream sequence
GACACTCCCCCGGCTCTGGCCTGGCGCCCGGAGACCAGTAGCAGCAGCTCCCCACGGCCGTTCACTGTGAGGGTGGGGAGGGCCGTGGGACCAGGAGGCC
Target sequence
CTTCCTGGCCTAGACGTGTGTGTCTTGctgtaattttggcgactggtgttggtggtgcccattttatggatggggaaggtcaaattccacagatattgagtgacaggcccagggccttggatttcagtgtttgactcagaacccaggtctctgatctgccaccagcctccctcccattCAGATGGGAACAGGGACTCCGGGCATGCAGTCTTCTCCCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate