Basic Information
VIS ID
TVIS30015573
Fusion event
HIV-TEPSIN integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79211652/81237852 (Hg38)
End
79211340/81237852 (Hg38)
Orient
-
Location type
Intronic
Target gene
TEPSIN
Nearest miRNA
hsa-mir-10226/Upstream/104544; hsa-mir-3186/Downstream/162864;
Nearest TSS
ENST00000595228/Upstream/254; ENST00000575067/Downstream/551;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/14233, chr17-CpG: 142/Downstream/764
Upstream sequence
ACCAGCATGTAAGGCTATTTGAAGGTACCTCTCCTGTACCTACCTACTGACTAGCAAAGCCAAACAAGGCCCAGGCAAGCCCCTTTTCCACACAGGGGAC
Downstream sequence
TATGAATCGTTCCACCTCCCCAGAGGCCGGAATGGCAGAGTGACAGCCGCTCAGCGTGACTAGCTCCATCGCTCCCCGAGAACCGACTGATGTCGTGTGT
Target sequence
AACGACCCACCTCTCACTGTTGACATGGCCGGAGAGAGGACTGGGAAGGGATGAGAACTGTGCTACTGGCCACAGGGAGGCTGCAGCAGGGTCCTCTCTCAACAGTCAGGGATGAACAGCCTCGGAGAAGAGGCAAATCAATGGTGGTTCTCCACGGAGGAGCTGCGCCACTTGGGTTAAGAAGGGACACAGCCCCCAGCCTCCCTGCACTTACCAGCATGTAAGGCTATTTGAAGGTACCTCTCCTGTACCTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate