Basic Information
VIS ID
TVIS30015574
Fusion event
HIV-FAAP100 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79510021/81542995 (Hg38)
End
79510171/81542995 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAAP100
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-423-3p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-10226/Upstream/91807; hsa-mir-4525/Downstream/150762;
Nearest TSS
ENST00000595228/Upstream/6849; ENST00000571914/Downstream/4208;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/5840, chr17-CpG: 141/Downstream/8795
Upstream sequence
TTTCCTCTGACAGGCAACACCTCAGCTCTGGAGAACCCCCTGGTGCCCCCAGCACTCAGGACTAGACCCCCAAGCCCAGGCAGCCCCATCGTGGTGCCGT
Downstream sequence
ACCTGCCAGGGCTGGGCAGAGCCACTGTTCACAGAAAGGCCTGGTCTCCAAGCATTACCACAGTGCCCACGGGAGTCAAGCTGGCGTCAGGCTGCAGGCC
Target sequence
GAGATCACTGGGGTCATGGTGCTGCGTGACATGCTCATCAGGGTCATGGCAGTGTCACAGTGCAGGGCACAGGGTCCTTGCACCAAATGAGATCTCTGGGTCATGGTGCTGCGTGAGTTGATGTGTTCATTGGGGTCGGCCATCTGAGCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate