Basic Information
VIS ID
TVIS30015576
Fusion event
HIV-FAAP100 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79511181/81544155 (Hg38)
End
79511609/81544155 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAAP100
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-423-3p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-10226/Upstream/92967; hsa-mir-4525/Downstream/149602;
Nearest TSS
ENST00000595228/Upstream/8009; ENST00000571914/Downstream/3048;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7000, chr17-CpG: 141/Downstream/7635
Upstream sequence
GAGCTTTCCACTTGAATCTCCACGGCCTGGATGGGCCCTGCTGGGCACAGGTCAGTCATGGCCACCTGCAACACAGGAGCCACCTCACTGCCTGCCTGTG
Downstream sequence
GCCTATCTATGGGACACCCACCTGTCCCTTAGGAAGGTTGGACTGAGCTGAGCTGGACAACAAATGGCAAGAACAGGCCAAGAGCCAGGAAGCCGGGCTT
Target sequence
GCACTCCCACCTGCCCGGGGGGCTCAGGCTACACAGGAGCCTCCCCAGCTGGCAGCACGTGAGGCCCTGAGATGGTCCCAACCCCCTGCCCTGGGCTGTCCTATACCCTGAAGGAGCAGAGCTCAGTACCCTGGTTTAGCTTTTTCCACCTGAAGAACCAGCCACCAACCAATGGCAAGAACCTGCTCTGTACCCAGGTGTGTCCAGGAAGACACCATCCCTCAGACCTGTGGAATTCACGCAGGGCCTCGAGCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate