Basic Information
VIS ID
TVIS30015577
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79800929/81843053 (Hg38)
End
79801160/81843053 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/149184; hsa-mir-4525/Downstream/393615;
Nearest TSS
ENST00000595228/Upstream/8003; ENST00000576784/Downstream/112;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/1305, chr17-CpG: 17/Downstream/3330
Nearby gene
P4HB(No orient, 104)
Upstream sequence
CAGGCAGGGAAGGCATCCTCCCCGGGAATCGCAAGCCTGCACAGCTCTGCTGGGGAGACTGGGGCCTGTTTCTGCATCTGCACCTCGTCCCAGGGGCGAG
Downstream sequence
AAGGGTCGTGGTTCTGCCTTGAACAGGCCACAGGCCGTGCTGTAGAGAGGCCAGTGGTCACAATGAGCCCACGACAGGAGGAGGAGCCCTGGCTTGAGGG
Target sequence
GCCTCTCAGCACCAGTAACCCCACTAAGGCCTGGCAGATGGCCTTGGCGTCCGCATTCCAGCCCAGCTCTCCGGGCTTGGTGAGATCATAAACCCGAGGCAAGGACAGGTGGTAAAATTTCAACTTTATTTGGCCAATGTGTTCAATTCGATTGTGAAATAGAAATGCCTGAAGAACTGTCAGCGTCTGATTCAGCTCCAGCATCCTTGGCCACCTCCCCACCCGGGAGTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate