Basic Information
VIS ID
TVIS30015580
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79824300/81866424 (Hg38)
End
79823970/81866424 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/172555; hsa-mir-4525/Downstream/370244;
Nearest TSS
ENST00000595228/Upstream/5730; ENST00000576021/Downstream/1297;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/5001, chr17-CpG: 57/Downstream/2504
Nearby gene
ARHGDIA(No orient, 1296)
Upstream sequence
GCAGCAACGCAACACGAGACCACCTCGCTTGGGGCTAGTAGCAGTTCTGGGAAAGGCTCGGTAGGGTCTTTGCTCCCTGCGGAATCAAGGGCTGGGGGCT
Downstream sequence
GACCCAGGCTTTCTCTATAGCTGCTTCCAGATCTGGGTCTGGACCAGCTTCTGCAGGAAGGCACCATTCTGTTGGGGTGTCTGACACGGTCAGCTCTAGG
Target sequence
GAAGGCCCTTGCCCGATGAGCCGAACTGCTGACAACACCCTGGCACTGGGCTTGGGGACTCCCCTGGAGCATGTAAGAAGTGAACTGGGAGCGTGGGAGAAACTGTCTGGCAGGGGCTGCTGCCTCGGAGCTCATCCTCCCTGGCTGTGCTGGTGTCTGTCCAGTGGGATTAGCCTCCATCCTGTGGTTTCACCACCCCACCGCCTCTCTCCCCCACAGCACAGGCAGAAGCAGCAACGCAACACGAGACCACCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate