Basic Information
VIS ID
TVIS30015582
Fusion event
HIV-CCDC57 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
80093462/82135586 (Hg38)
End
80093663/82135586 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC57
miRNAs that regulate target gene
hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10226/Upstream/441717; hsa-mir-4525/Downstream/101082;
Nearest TSS
ENST00000595228/Upstream/1243; ENST00000579979/Downstream/16020;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/8129, chr17-CpG: 119/Downstream/76860
Upstream sequence
CATCGCAGGATTAGCTCTGCCCTGTGGACATCCCGAGATGGGCCCTCAAGTAAAGCATCAGTTTCTTCTACGCAATAAAAGAACCCAAAGATGACACTTG
Downstream sequence
ggtggctcacacctgtaaccccagcacactgggaggccgggtgggggggatccttgatgtcaggtgttggatactggcgtgggcaacacagtgagatccc
Target sequence
GAAATGAACGTGTTTCCCTTGGTTTATAAACACCTGAATTTAAAAGCCATGAAGTCagaagatgcacgtgtgggcaaaaacctcctgaagacactcaacaccattggtcaccaggagaatgtaaaatcaagcccactatgggatcccgcctcacacccactaggttggctgggatcaacaggatagaaaacagctgggtgc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate