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TVIS30015590
Basic Information
VIS ID
TVIS30015590
Fusion event
HIV-FOXK2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
80504490/82546614 (Hg38)
End
80504755/82546614 (Hg38)
Orient
+
Location type
Intronic
Target gene
FOXK2
miRNAs that regulate target gene
hsa-mir-122-5p
;
hsa-mir-769-5p
;
hsa-mir-425-5p
;
hsa-mir-18a-3p
;
hsa-mir-183-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-7-5p
;
hsa-mir-106b-5p
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-302c-3p
;
hsa-mir-302d-3p
;
hsa-mir-372-3p
;
hsa-mir-373-3p
;
hsa-mir-20b-5p
;
hsa-mir-520e
;
hsa-mir-520f-3p
;
hsa-mir-520a-3p
;
hsa-mir-526b-3p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-519d-3p
;
hsa-mir-520d-3p
;
hsa-mir-636
;
hsa-mir-302e
;
hsa-mir-3166
;
hsa-mir-3607-3p
;
hsa-mir-3686
;
hsa-mir-6077
;
hsa-mir-1273h-3p
;
hsa-mir-4264
;
hsa-mir-3613-3p
;
hsa-mir-6079
;
hsa-mir-3646
;
hsa-mir-4694-3p
;
hsa-mir-222-5p
;
hsa-mir-504-3p
;
hsa-mir-4765
;
hsa-mir-4797-3p
;
hsa-mir-3129-5p
;
hsa-mir-199b-3p
;
hsa-mir-199a-3p
;
hsa-mir-936
;
hsa-mir-6514-5p
;
hsa-mir-365b-3p
;
hsa-mir-365a-3p
;
hsa-mir-3184-3p
;
hsa-mir-3667-5p
;
hsa-mir-203a-3p
;
hsa-mir-4771
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-2861
;
hsa-mir-6811-3p
;
hsa-mir-6735-3p
;
hsa-mir-5681a
;
hsa-mir-5092
;
hsa-mir-4512
;
hsa-mir-6749-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-1248
;
hsa-mir-5193
;
hsa-mir-4667-3p
;
hsa-mir-6865-3p
;
hsa-mir-5088-3p
;
hsa-mir-6512-5p
;
hsa-mir-4790-3p
;
hsa-mir-152-5p
;
hsa-mir-182-3p
;
hsa-mir-218-2-3p
;
hsa-mir-224-3p
;
hsa-mir-4743-3p
;
hsa-mir-522-3p
;
hsa-mir-548ao-5p
;
hsa-mir-548ax
;
hsa-mir-5585-5p
;
hsa-mir-5680
;
hsa-mir-597-3p
;
hsa-mir-6888-3p
Nearest miRNA
hsa-mir-10226/Upstream/309886; hsa-mir-4525/Downstream/121619;
Nearest TSS
ENST00000595228/Upstream/26320;
ENST00000531030/Downstream/12726;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/25937
,
chr17-CpG: 58/Downstream/29271
Upstream sequence
TGCACATGCAGGAGCTCTTCGCTGCAGGTCCCGAGTGGAGGGAGAGGTAATCTGTAGAGTGCCCCAAGAGTGAAGTGCTGCGTCCCAGTGTCAAACAGAG
Downstream sequence
catcccgcccaacatggtgaaaccccgtctctactaaaaataccaaaattagtcgggcgtggtggtgggtgcctgtagtcccagctactctggaggctga
Target sequence
GTAACACCTCGCTTTtcttttccttttttttaaacggtgacgggggtctcaccatgttgcccaggctggtcttgaactcctgggctcaagtgttcctcccacctcagactcccaagttcagggataataggtgtaagccactgagcccaaccTAAAACTCGCTTTTAAATAAAGAACTCAggccgggtgcggtggctcacacctggaatcccagcactttgggaggccgaggcagatggatcacctgaggtcagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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