Basic Information
VIS ID
TVIS30015592
Fusion event
HIV-SMCHD1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
End
2706274/2706189 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-8078/Upstream/2593850; hsa-mir-1-2/Downstream/1179164;
Nearest cancer related gene
SMCHD1(TSG, No orient, 0)
Upstream sequence
ccagaattctatctcagcaatgagtaactacaaaactggagtgggttttttccctataccatgctTTCTTGTTAATGTTTGATATGTTAGGACTACAGAG
Downstream sequence
CTTTGGAAGAAACAAATGGGTGTTTGTTTTTATTACAGCTAGATTTAAATAGTTTTCTTTGAAATGTTGGTAAATGTATTTATTCAGGAACCTCAGGCAC
Target sequence
GTTATATAAAAAATATAAACAAACATTGTGGTGTAACGTAAGAATAGCTACTGTTATTTATGTACTTAATTAGGATAAAATATATTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate