Basic Information
VIS ID
TVIS30015595
Fusion event
HIV-LPIN2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
2970328/2970330 (Hg38)
End
2970403/2970330 (Hg38)
Orient
+
Location type
Intronic
Target gene
LPIN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-769-5p
Nearest miRNA
hsa-mir-8078/Upstream/2857991; hsa-mir-1-2/Downstream/915023;
Nearest TSS
ENST00000575820/Upstream/3312; ENST00000580139/Downstream/12479;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/57021, chr18-CpG: 105/Downstream/42219
Upstream sequence
AGGGCTCCCTGGATTTCAATGATTTCAGTGCTCAGAGAGGCACCGAAACACAAGGGTGGGCCCCCAGTAGCCATGTCTATAATACGGGACCCAGGTCTTG
Downstream sequence
CCACCCAAGACTGGGAGGGCTGGGCTACCTGAGATGGGATGCAGAAGGCCCACCAGCTTGGAACACTGACACCCCAGGTGGCCCTGGCTCTTGCCCTCTT
Target sequence
GTATCTGCTGGCTGACAGGGGTGGGAAACATCTGGCCCAAACAGATATTCATGAAACGTATATGGAGAGCCAAGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate