Basic Information
VIS ID
TVIS30015599
Fusion event
HIV-ANKRD12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
9235426/9235428 (Hg38)
End
9235328/9235428 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANKRD12
miRNAs that regulate target gene
hsa-mir-342-5p ; hsa-mir-365a-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-374a-5p ; hsa-mir-155-5p ; hsa-mir-1273e ; hsa-mir-3692-3p ; hsa-mir-140-3p ; hsa-mir-144-3p
Nearest miRNA
hsa-mir-3976/Upstream/2861003; hsa-mir-1-2/Downstream/1524156;
Nearest TSS
ENST00000575820/Upstream/18648; ENST00000581641/Downstream/99013;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/97832, chr18-CpG: 134/Downstream/98470
Upstream sequence
aaaacaaaaaTTGAATAggaagaaaaatcatttatcttgccttcgttatatgaactctgtcactggataatttcatcataggtaaagagaagtatcttta
Downstream sequence
taatattaatccagctaaaaagaaaaaaagttaaaatattactattttgccatagttaatatatctctaagcattgaatatcaacagttgctaacaccac
Target sequence
aacaaaaaTTGAATAggaagaaaaatcatttatcttgccttcgttatatgaactctgtcactggataatttcatcataggtaaagagaagtatcttta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate