VISDB Viral Integration Site DataBase

VIS ID

TVIS30015600

Fusion event

HIV-SPIRE1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr18

Cytoband

p11.21

Reference genome

Start

End

12612506/12611932 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-151a-5p ; hsa-mir-186-5p ; hsa-mir-101-3p ; hsa-mir-769-5p ; hsa-mir-484 ; hsa-mir-99a-5p ; hsa-mir-218-5p ; hsa-mir-215-3p ; hsa-mir-6777-3p ; hsa-mir-3976 ; hsa-mir-369-3p ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-510-5p ; hsa-mir-4662a-3p ; hsa-mir-374c-5p ; hsa-mir-655-3p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181d-5p ; hsa-mir-4262 ; hsa-mir-181b-5p

Nearest miRNA

hsa-mir-3976/Upstream/956991; hsa-mir-1-2/Downstream/848015;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/177445, chr18-CpG: 198/Downstream/45113

Upstream sequence

ttctttttttttttgtattttagtagagaagaagtctcactatgttggccaggctggtctcaaactcctgagctcaagtgatcctcctgcctccgcctcc

Downstream sequence

aaggccctatatccttactaatcaaactgtggtcccaggaccagtaacttcaccgtcacctgagggtttgttatctctgacccaactcaagatctaccaa

Target sequence

caaagtgctgagattacaggcgtgagccactgtgcccagcttaatttgttatgtagcaatagatatctaacataCACAccctttacaaaaaaatgcctcagtaacttttatttattcactatctctgatttctctcctctcttctctttgaaacccactccaataagccttttgccctcacgctacccagctacctgcttgtcaataaccactatgttgtcaaactcaataatcaattcttagctttcctcttac