Basic Information
VIS ID
TVIS30015604
Fusion event
HIV-chr18 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
19305668/21725707 (Hg38)
End
19305611/21725707 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3156-2/Upstream/42118; hsa-mir-1-2/Downstream/99991;
Nearest TSS
ENST00000575820/Upstream/20750; ENST00000577749/Downstream/15613;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/20616, chr18-CpG: 140/Downstream/14921
Nearby gene
MIB1(No orient, 15876)
Upstream sequence
AGACTATCTTCCTCTGGAGGGGATTAATTTACAGACTATAACCTAACTGGACAAACATAAAGTAAATAAAAGCTTCCTCTTCCTCCTTCCCGAGGGGAAA
Downstream sequence
GTCAAAGACACACTTTGTGTAAGATTGAAAGACAGTTGAACaggaaggaaggaaggaaggagggagggagggagagagggaaggaaggaaggaaggaagg
Target sequence
TAACTGGACAAACATAAAGTAAATAAAAGCTTCCTCTTCCTCCTTCCCGAGGGGAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate