VISDB Viral Integration Site DataBase

VIS ID

TVIS30015607

Fusion event

HIV-CABLES1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr18

Cytoband

q11.2

Reference genome

Start

End

20792398/23212255 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-let-7e-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-4531 ; hsa-mir-4737 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-381-5p ; hsa-mir-140-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-6802-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-1-2/Upstream/278817; hsa-mir-122/Downstream/1109420;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/75148, chr18-CpG: 30/Downstream/225452

Nearest cancer related gene

CABLES1(TSG, No orient, 0)

Upstream sequence

ACAGAGGTCTGAAGAGGTTCTGAGTCCATGGACTAGGCTGGAAAACCTGAATCCTAACCCAGGCAGCTGGTCTGCAGTAAAGATGGTTCatatttattga

Downstream sequence

ctgagtgtgttactttggtcccatcccattaaccactGGGGATATGAACTGCTATGGAATTGACACCAAAAGTGCCAAAAGCCGAAAGTGGCTTTTGATT

Target sequence

gtgtgtactatttgccagctgctcttctgagggttctccaagtatgggctcatgtactcttacagcattccaataagatagttactaattttatcccattttttagaagggcagaatgaggctcagaagtgttagtaagctgaccgaggtcaaacaaaagtgacagctggtgttcgaag