Basic Information
VIS ID
TVIS30015608
Fusion event
HIV-PSMA8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23719147/26139183 (Hg38)
End
23719006/26139183 (Hg38)
Orient
-
Location type
Intronic
Target gene
PSMA8
Nearest miRNA
hsa-mir-1-2/Upstream/1817437; hsa-mir-122/Downstream/452284;
Nearest TSS
ENST00000575820/Upstream/5306; ENST00000612461/Downstream/903;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/5194, chr18-CpG: 105/Downstream/87136
Upstream sequence
acttagtgacttgcttttaaggaatggaataggtgaaaatgacgaatgtcacatcagggattaggttgcaaagaaatggtgacttcattttattcatcct
Downstream sequence
tactcgctgttttgcttgcttactctggtgaaacccagctgccgtgttgagttgccctctgcagggcccaatgaggcaaggaactgagggaaacatttgt
Target sequence
tcatgcccttgtataaccttcctcccttggatgtgggctgaacttagtgacttgcttttaaggaatggaataggtgaaaatgacgaatgtcacatcagggattaggttgcaaagaaatggtgacttcattttattcatcct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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