Basic Information
VIS ID
TVIS30015609
Fusion event
HIV-CDH2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
25559558/27979594 (Hg38)
End
25559515/27979594 (Hg38)
Orient
-
Location type
Intronic
Target gene
CDH2
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-194-5p ; hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-27b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-199a-5p ; hsa-mir-412-3p ; hsa-mir-411-5p ; hsa-mir-216b-3p ; hsa-mir-1244 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-338-3p ; hsa-mir-506-3p ; hsa-mir-153-5p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-587
Nearest miRNA
hsa-mir-1-2/Upstream/1388059; hsa-mir-122/Downstream/2319316;
Nearest TSS
ENST00000575820/Upstream/25075; ENST00000582726/Downstream/56991;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/794051, chr18-CpG: 257/Downstream/195856
Upstream sequence
aaaatgcaccagaacatatgcacacaaatgttcataacagttttattcataataacccaactggaaaacctcaagtgcccaagtgaagtaggatggatac
Downstream sequence
ataaaatgtagttaattcttccaacagaatactattcagcagtgacaaaaatgaacgacttctacacatgaatctcacaggtacaatgttgagtaataga
Target sequence
caactggaaaacctcaagtgcccaagtgaagtaggatggatac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate