Basic Information
VIS ID
TVIS30015611
Fusion event
HIV-IER3IP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
44695083/47168712 (Hg38)
End
44695231/47168712 (Hg38)
Orient
+
Location type
Intronic
Target gene
IER3IP1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-155-5p ; hsa-mir-10a-5p ; hsa-mir-107 ; hsa-mir-19b-3p ; hsa-mir-423-3p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-1229-3p ; hsa-mir-302c-5p ; hsa-mir-218-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-29b-1-5p ; hsa-mir-153-5p ; hsa-mir-577 ; hsa-mir-504-5p ; hsa-mir-6882-5p ; hsa-mir-6732-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130a-3p ; hsa-mir-7977 ; hsa-mir-676-5p ; hsa-mir-138-1-3p ; hsa-mir-4267 ; hsa-mir-552-5p ; hsa-mir-500a-3p ; hsa-mir-197-3p ; hsa-mir-431-5p ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6832-3p ; hsa-mir-4709-5p ; hsa-mir-1285-5p ; hsa-mir-140-3p ; hsa-mir-216a-5p ; hsa-mir-212-3p ; hsa-mir-132-3p
Nearest miRNA
hsa-mir-1-2/Upstream/2198546; hsa-mir-122/Downstream/211784;
Nearest TSS
ENST00000575820/Upstream/18192; ENST00000565127/Downstream/7568;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/18026, chr18-CpG: 43/Downstream/7339
Upstream sequence
ttatgcagcattccattatatgaatacaatttagtcattctaccatttctaattttcattatgattatgctgctatgaacattctcatacatgtcttttg
Downstream sequence
ttctataaccttatcaaaacttcctattttcAGGTAAGAATGTGTAATTCAAAAAACAAACAAAGACCCTCCAGCTTTCTGGataccttacaattcatac
Target sequence
gtgcacatatttatgagcatttgtataagagtgaaactgtaggaccatagaagatgtgtatgatgagctttagttacttctgccaaaaagtttttcaaagtggttgtgccaatttatacttccatcagcagagtatgagttcacactg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate