Basic Information
VIS ID
TVIS30015613
Fusion event
HIV-chr18 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
48375221/50848851 (Hg38)
End
48375243/50848851 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/722288; hsa-mir-122/Downstream/2388250;
Nearest TSS
ENST00000575820/Upstream/23449; ENST00000638768/Downstream/29883;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/118862, chr18-CpG: 109/Downstream/29914
Nearby gene
MRO(No orient, 23467)
Upstream sequence
ctcctgcctcagtctcccgagtagctgggattacaggcacctgccaccacgcctagttaatttttgtatttttagtagaaatgaggtttcaccatgttgg
Downstream sequence
cctcaggtgatccgcccaccttggcctcccaaactgctaggattacaggcgtgagccaccgtacctggccAGAAGTCTTTTATTTTGACAAAAGAAGGAG
Target sequence
ccaggctagtcttaactcctga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate