Basic Information
VIS ID
TVIS30015620
Fusion event
HIV-ZNF407 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
72659708/74947752 (Hg38)
End
72659752/74947752 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF407
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1-2/Upstream/2094370;
Nearest TSS
ENST00000575820/Upstream/70547; ENST00000582214/Downstream/112403;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/349024, chr18-CpG: 23/Downstream/139935
Nearby gene
ZNF407(No orient, 143125)
Upstream sequence
ACCAGTGCTGTCATCCTGGCAACGGTGCCAAGATCAGAGTCAGCCTCACTCAACTGATAAAAGCCCTGTACAGACAAACAGGTAGGCAGGACCTGTGCGT
Downstream sequence
TGTCTTTCAAAGAACAGTGGGCTTTCTCCCTGCGCCTTTTGTTTCTACTTACTTCCTCTCATTTCTTTTCTCCATTTCTTATGACCTCTCAGCTCCCTCT
Target sequence
GTAGCCCACCATTTTCCTTCAATGAAAGTGAAGCGCTAAGCCTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate