Basic Information
VIS ID
TVIS30015622
Fusion event
HIV-PTBP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
End
810854/810990 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-124-3p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-378a-3p ; hsa-mir-15b-5p ; hsa-mir-92a-3p ; hsa-mir-30a-5p ; hsa-mir-17-3p ; hsa-mir-17-5p ; hsa-mir-340-5p ; hsa-mir-374a-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-5582-5p ; hsa-mir-548n ; hsa-mir-548t-5p ; hsa-mir-4476 ; hsa-mir-548az-5p ; hsa-mir-6830-5p ; hsa-mir-6876-5p ; hsa-mir-194-5p ; hsa-mir-624-3p ; hsa-mir-802 ; hsa-mir-3163 ; hsa-mir-4457 ; hsa-mir-329-5p ; hsa-mir-506-3p ; hsa-mir-605-3p ; hsa-mir-657 ; hsa-mir-940 ; hsa-mir-3714 ; hsa-mir-4736 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-7856-5p ; hsa-mir-4477b ; hsa-mir-647 ; hsa-mir-6762-3p ; hsa-mir-4440 ; hsa-mir-604 ; hsa-mir-671-5p ; hsa-mir-4480 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-4786-3p ; hsa-mir-1205 ; hsa-mir-3691-3p ; hsa-mir-3910 ; hsa-mir-659-5p ; hsa-mir-127-5p ; hsa-mir-670-5p ; hsa-mir-4467 ; hsa-mir-1273a ; hsa-mir-3934-3p ; hsa-mir-4707-3p ; hsa-mir-6087 ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-6734-3p ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-7108-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-6798-5p ; hsa-mir-6854-5p ; hsa-mir-133b ; hsa-mir-1199-3p ; hsa-mir-1292-3p ; hsa-mir-1908-3p ; hsa-mir-3648 ; hsa-mir-6076 ; hsa-mir-6797-3p ; hsa-mir-6869-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/5989; hsa-let-7e/Downstream/2594;
Upstream sequence
TTAAAAACAGCTGAAGTGACCTTAGCAGACCAGAGATTTTATTTTTTTAAAGAGAAATCAGTTTACCTGTTTTTAAAAAAATTAAATCTAGTTCACCTTG
Downstream sequence
CTCACCCTGCGGTGACAGGGACAGCTCAGGCTCTTGGTGACTGTGGCAGCGGGAGTTCCCGGCCCTCCACACCCGGGGCCAGACCCTCGGGGCCATGCCT
Target sequence
TGGCGACAACTTCCATCATTCCAGAGAAAAGCCACTTTAAAAACAGCTGAAGTGACCTTAGCAGACCAGAGATTTTATTTTTTTAAAGAGAAATCAGTTTACCTGTTTTTAAAAAAATTAAATCTAGTTCACCTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate