Basic Information
VIS ID
TVIS30015634
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2741344/2741346 (Hg38)
End
2741194/2741346 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-1227/Upstream/110553; hsa-let-7e/Downstream/1220068;
Nearest TSS
ENST00000633603/Upstream/1194; ENST00000586780/Downstream/18196;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/951, chr19-CpG: 34/Downstream/13201
Nearby gene
SLC39A3(No orient, 1270)
Upstream sequence
caagcgtccataaggaaccaaatgctaccaacagccatgaacgtgatcatggaagagggtcctgccccagttgagcctttggatgactgcttcacttcaa
Downstream sequence
ttgcagcctttgaaacaccctaaaacagggctgcatgtggtagctcatgcctataatcccagcactttggaaggccgaggtaggcaggtcacttaaagtc
Target sequence
ctgagggtgtcctccagccaacagtcagcaaggcaatgagaccctcagcacaagcgtccataaggaaccaaatgctaccaacagccatgaacgtgatcatggaagagggtcctgccccagttgagcctttggatgactgcttcacttcaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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