Basic Information
VIS ID
TVIS30015636
Fusion event
HIV-ZNF555 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2844520/2844522 (Hg38)
End
2844625/2844522 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ZNF555
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-let-7a-5p ; hsa-mir-4799-5p ; hsa-mir-4255 ; hsa-mir-1264 ; hsa-mir-3184-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-5692a ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-665 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4724-5p ; hsa-mir-125b-2-3p ; hsa-mir-1262 ; hsa-mir-1273g-3p ; hsa-mir-3120-5p ; hsa-mir-3664-5p ; hsa-mir-4252 ; hsa-mir-4457 ; hsa-mir-4522 ; hsa-mir-4701-3p ; hsa-mir-4705 ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-513b-5p ; hsa-mir-542-3p ; hsa-mir-6510-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6888-3p ; hsa-mir-766-3p ; hsa-mir-7703
Nearest miRNA
hsa-mir-1227/Upstream/213729; hsa-let-7e/Downstream/1116892;
Nearest TSS
ENST00000633603/Upstream/3078; ENST00000586470/Downstream/14194;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2307, chr19-CpG: 27/Downstream/14373
Upstream sequence
gatacagggttttgccatgttggccaggctggtctcgaactcctgacctcaggtggcccgcccgcctcagcctccccgagtgctggaattataggtgtga
Downstream sequence
tttagggtaaacacattgttgcataaacagtttcagcacaataagcaactcctctattgggatgagaaccctccccaaatccaggctagcttatgccagc
Target sequence
accaccatgcccCCAAccagggtgttttaaaattggcggctggtcacagaggtcccctgtgcctggctgtgccaagatttcagacacccaggaggaaagcagatc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate