Basic Information
VIS ID
TVIS30015644
Fusion event
HIV-BMP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
7697357/7632471 (Hg38)
End
7697426/7632471 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA19B
Target gene
BMP1
miRNAs that regulate target gene
hsa-mir-29b-3p ; hsa-mir-335-5p ; hsa-mir-194-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1227/Upstream/14966; hsa-let-7e/Downstream/756819;
Nearest TSS
ENST00000633603/Upstream/1946; ENST00000597467/Downstream/500;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2760, chr19-CpG: 65/Downstream/4304
Upstream sequence
CATCGCCAGAACATCACCTACCTTGGACCCCACGGGCTGGAAGCCGGGCAGGCTGCTGACTGTCACACGTTGGTCATCCATGCGGCGGCCCTGGGTACTG
Downstream sequence
GGAGGACACAGCCGGAGTGGGGGCCCCCAACCCTACCCCTTCACCCCCACACAGATGCTTCAGGGTGCACAACCACCTCCCACATCCCGTGCCCCCAGGC
Target sequence
GCCAGCATGTCCATGAGGCTGTCCATCTCGGGGGTGGGGTCGCTCTCTGCGTGGACGTTCACAGACTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate