Basic Information
VIS ID
TVIS30015649
Fusion event
HIV-HNRNPM integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
End
8526828/8462308 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1227/Upstream/72928; hsa-let-7e/Downstream/1576046;
Upstream sequence
TCACGCAGACTTCTTTCCTATAGATTTGGATTGCCTCTAGTCATGAATGAGTCTTCCAGACAGGGAAATTGATACGGAAATCTGTGGAATAGCTTGTTTG
Downstream sequence
TGGTGGGAGGAAAATCAAGGACATATTGTTAACGTGTTTTCACCTACTTTTACTGCACACCTGTAATGCCTAGTTCGGTGGTTTAGAGAATATGGAGTGT
Target sequence
aagaatgtcatggcagcgataacagcattaaaccaagctcagggcccctgagtgcggggctctgtacaattgcacgagttgctcacctgtgaagctggccctgCGGCCGTGTGTGCCTGTGAGCTTATACCTTCGCATACGTGCGTCCTTGTATTTATAGCATGTGAGCTCAGCCCGATGGCATCGCAATTTGTATGCATTTCACCTGCTTGCCACCAATGAGAGCGTATGTGTAAAACCTCCTCCCTTCCCCAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate