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TVIS30015687
Basic Information
VIS ID
TVIS30015687
Fusion event
HIV-CARM1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
11021283/10910607 (Hg38)
End
11021184/10910607 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
CARM1
miRNAs that regulate target gene
hsa-mir-92a-3p
;
hsa-let-7e-5p
;
hsa-mir-15a-5p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-181c-5p
;
hsa-mir-181d-5p
;
hsa-mir-149-3p
;
hsa-mir-1207-5p
;
hsa-mir-1909-3p
;
hsa-mir-4728-5p
;
hsa-mir-4763-3p
;
hsa-mir-6722-3p
;
hsa-mir-6785-5p
;
hsa-mir-6883-5p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-1249-5p
;
hsa-mir-3688-3p
;
hsa-mir-5093
;
hsa-mir-6721-5p
;
hsa-mir-6757-5p
;
hsa-mir-6797-5p
;
hsa-mir-7112-5p
;
hsa-mir-223-3p
;
hsa-mir-1245b-5p
;
hsa-mir-1296-3p
;
hsa-mir-184
;
hsa-mir-194-3p
;
hsa-mir-3142
;
hsa-mir-4297
;
hsa-mir-5581-5p
;
hsa-mir-6734-3p
;
hsa-mir-6742-5p
;
hsa-mir-128-1-5p
;
hsa-mir-128-2-5p
;
hsa-mir-15b-5p
;
hsa-mir-16-5p
;
hsa-mir-1827
;
hsa-mir-195-5p
;
hsa-mir-3131
;
hsa-mir-424-5p
;
hsa-mir-4283
;
hsa-mir-4436a
;
hsa-mir-451b
;
hsa-mir-4700-3p
;
hsa-mir-497-5p
;
hsa-mir-5000-3p
;
hsa-mir-542-5p
;
hsa-mir-611
;
hsa-mir-6777-5p
;
hsa-mir-6808-5p
;
hsa-mir-6838-5p
;
hsa-mir-6877-5p
;
hsa-mir-6889-5p
;
hsa-mir-6893-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-1181/Upstream/81572; hsa-let-7e/Downstream/202867;
Nearest TSS
ENST00000633603/Upstream/38697;
ENST00000586508/Downstream/8379;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/38017
,
chr19-CpG: 47/Downstream/10650
Upstream sequence
TATTCCCTTCTCATCCCATTTGCCAGAGTTTTTGGTGTCTACCTTttttatttttttatttttacttttttttttatgagatggagtcttgctttgttac
Downstream sequence
caggctggagtgcagtgacacaatctcggctcactgcaacctccgcctcccgggttcaagcaattctcctgcctcagcctcctgagtagctgggactaca
Target sequence
ATTCCCTTCTCATCCCATTTGCCAGAGTTTTTGGTGTCTACCTTttttatttttttatttttacttttttttttatgagatggagtcttgctttgttac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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