Basic Information
VIS ID
TVIS30015689
Fusion event
HIV-LDLR integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
End
11230865/11120066 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-130a-3p ; hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-30a-5p ; hsa-mir-19b-3p ; hsa-let-7b-5p ; hsa-mir-744-5p ; hsa-mir-26b-3p ; hsa-mir-92b-3p ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-mir-27a-3p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-519a-3p ; hsa-mir-605-5p ; hsa-mir-548c-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-4301 ; hsa-mir-4286 ; hsa-mir-3613-3p ; hsa-mir-3666 ; hsa-mir-4668-3p ; hsa-mir-4803 ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-27b-3p ; hsa-mir-181d-5p ; hsa-mir-506-5p ; hsa-mir-641 ; hsa-mir-4262 ; hsa-mir-3617-5p ; hsa-mir-4708-3p ; hsa-mir-6867-5p ; hsa-mir-216a-3p ; hsa-mir-1468-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-4251 ; hsa-mir-3681-3p ; hsa-mir-4428 ; hsa-mir-548aj-5p ; hsa-mir-4539 ; hsa-mir-4681 ; hsa-mir-203b-3p ; hsa-mir-4786-5p ; hsa-mir-548aw ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-let-7f-2-3p ; hsa-mir-98-3p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-187-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-140-5p ; hsa-mir-190a-3p ; hsa-mir-495-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-548d-3p ; hsa-mir-1185-2-3p ; hsa-mir-1283 ; hsa-mir-1185-1-3p ; hsa-mir-450b-5p ; hsa-mir-548h-3p ; hsa-mir-1284 ; hsa-mir-3121-3p ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-5011-5p ; hsa-mir-5688 ; hsa-mir-548bb-3p ; hsa-mir-539-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-410-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-377-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-1228-3p ; hsa-mir-4284 ; hsa-mir-2276-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-6890-3p ; hsa-mir-299-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-199a-5p ; hsa-mir-1972 ; hsa-mir-2277-3p ; hsa-mir-449b-3p ; hsa-mir-4691-3p ; hsa-mir-4717-5p ; hsa-mir-6511b-5p ; hsa-mir-6741-5p ; hsa-mir-6742-3p ; hsa-mir-6765-3p ; hsa-mir-6776-5p ; hsa-mir-6811-5p ; hsa-mir-7851-3p ; hsa-mir-1229-5p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-197-5p ; hsa-mir-205-3p ; hsa-mir-2392 ; hsa-mir-3132 ; hsa-mir-3133 ; hsa-mir-3605-5p ; hsa-mir-3687 ; hsa-mir-3913-3p ; hsa-mir-3942-3p ; hsa-mir-4442 ; hsa-mir-4709-5p ; hsa-mir-4795-5p ; hsa-mir-5094 ; hsa-mir-548b-3p ; hsa-mir-593-3p ; hsa-mir-6716-5p ; hsa-mir-6746-5p ; hsa-mir-6771-5p ; hsa-mir-6782-5p ; hsa-mir-6818-3p ; hsa-mir-6845-3p ; hsa-mir-6894-5p ; hsa-mir-6895-3p ; hsa-mir-7106-5p ; hsa-mir-7704 ; hsa-mir-802 ; hsa-mir-8053
Nearest miRNA
hsa-mir-1181/Upstream/6532; hsa-let-7e/Downstream/375478;
Upstream sequence
tctgtctgaaacaaacaaacaaacaaacaaacagacaaacaaaaaaacTAGTTGTGGAGAGAGGGTGGCCTGTGTCTCATCCCAGTGTTTAACGGGATTT
Downstream sequence
CCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGTAAGGGTGGGTCAGCCCCACCCCCCCAACCTTGAAACCTCCTTGTGGAAACTCTG
Target sequence
GTCATCTTCCTTGCTGCCTGTTTAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate