Basic Information
VIS ID
TVIS30015697
Fusion event
HIV-chr19 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
13283554/13172740 (Hg38)
End
13283441/13172740 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/232200; hsa-let-7e/Downstream/663547;
Nearest TSS
ENST00000633603/Upstream/18547; ENST00000587098/Downstream/41811;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/9438, chr19-CpG: 93/Downstream/34492
Nearby gene
IER2(No orient, 17836)
Upstream sequence
TGTCAAGACCATCCACACTGCCCTCTCCTGCTTCCTCCTCCTCTACCCGCCCTCTTTCAGTGGGATTTTTTTTTCCGGGTACCACGCTAGGGCAGGAAGG
Downstream sequence
CAGAAGTGAGCATGGGGCGTGGAACGTCTCTGAGGTTGGAATATATTTAGGCCAGGAGAAGAGTGTGTGTGTGGTGCTGGCCAGGCCCTGGCGCCGGCTC
Target sequence
CCTTGAGGCCACATGTCAAGACCATCCACACTGCCCTCTCCTGCTTCCTCCTCCTCTACCCGCCCTCTTTCAGTGGGATTTTTTTTTCCGGGTACCACGCTAGGGCAGGAAGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate